Catalysis & Chemical Biology Lab
Prof. Sharada's
Publications..
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Srilaxmi M. Patel, Prasad Paradakshini, Manickam Bakthadoss and Duddu. S. Sharada. Photocatalytic Visible-Light-Induced Nitrogen Insertion via Dual C(sp3)–H and C(sp2)–H Bond Functionalization: Access to Privileged Imidazole-based Scaffolds Org. Lett. 2021,23, 257−261
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Anand H. Shinde, Venkata Nagarjuna Babu, Narenderreddy Katta and Duddu. S. Sharada. Aluminium-Mediated Isocyanide Insertion and Sequential Ring Opening Cyclization (SROC) Strategy: Synthesis of Azole-Fused Benzimidazoquinazoline Skeletons Org lett. 2020 (Under Revision)
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Manickam Bakthadoss, Tadiparthi Tirpath Reddy, and Duddu. S. Sharada. Ruthenium-catalyzed, Site-Selective C-H activation: Access to C5-substituted azaflavanone RSC Adv., 2020,10, 31570-31574.
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Narenderreddy Katta, Mamatha Ojha, Armugavel Murgan, Sagar Arepally. Duddu. S. Sharada. Visible light-mediated photocatalytic oxidative cleavage of activated alkynes via hydroamination: a direct approach to oxamates†action RSC Advance, 2020,10, 12599-12603.
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Ruthenium mediated chemo and site-selective C–H amidation of oxobenzoxazine derivatives with sulfonyl azides. New Journal of Chemistry. 2019. 43, 14190-14195.
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Three Component, One-Pot Synthesis Of Multifunctional Quinolinopyranpyrazoles Via Catalyst-Free Multicomponent Reaction. Chem. Select. 2019, 4, 7996 - 7999.
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Regioselective C3-H trifluoromethylation of 2H-indazole under transition-metal-free photoredox catalysis J. Org. Chem. 2019. 84, 7796-7803
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Exocyclic N-Acyliminium ion (NAI) Cyclization: Access to Fully Substituted Oxazoles and Furocoumarins J. Org. Chem. 2019, 84,6631-41
Srilaxmi M. Patel, Harika CH, Sonali Biswal, Sonika Sharma and Duddu, S. Sharada. Copper-Catalyzed Intramolecular α-C‒H Amination via Ring-Opening Cyclization Strategy to Quinazolin-4-ones: Development and Application in Rutaecarpine Synthesis”
Synthesis, 2019, 51, 3160-3170.
Sagar Arepally, Narenderreddy Katta, Ajoy Chamuah, Duddu, S. Sharada.Stereoselective Aminoiodination of Activated Alkynes with Organoiodine(III) Reagents and Amines via Multiple-Site Functionalization: Access to Iodinated Enamines and N-Aryl Indoles. Eur. J. Org. Chem. 2019, 7, 1542-1547. [This article is denoted as Very Important Paper (VIP)].
Manickam Bakthadoss, Srinivasan Jayakumar, Selavakumar Raman, Anthonisamy Devaraj, and Duddu, S. Sharada.
A Novel Multicomponent Quadruple/Double Quadruple Domino Reaction: Highly Efficient Synthesis of Polyheterocyclic Architectures Org. Biomol. Chem., 2019,17, 3884-3893 (Accepted Cover Page )
Manickam Bakthadoss, Polu Vijay Kumar , Tadiparthi Thirupathi Reddy, Duddu, S. Sharada. Solvent and catalyst-free ring expansion of Indoles: A simple synthesis of highly functionalized Benzazepines. Org. Biomol. Chem., 2018,16, 8160-8168
Sagar Arepally, Venkata Nagarjuna Babu, Ashok Polu, Duddu S. Sharada. PIDA/TBAB-Promoted Oxidative Geminal Dibromofunctionalization of Alkynes: Direct Synthesis of Geminal Diazides. Eur. J. Org. Chem. 2018 41, 5700-5705
Arumugavel Murugan, Koteswar Rao Gorantla, Bhabani S. Mallik, Duddu S. Sharada. Iron Promoted C3-H Nitration of 2H-Indazole: Direct access to 3- Nitro-2H-Indazoles. Org. Biomol. Chem. 2018,16, 5113-5118​.
Srilaxmi M. Patel, Kuntal Pal, P. Naresh Kumar, Melepurath Deepa, Duddu S. Sharada. Design and Synthesis of Novel Indole and Carbazole Based Organic Dyes for Dye-Sensitized Solar Cells: Theoretical Studies by DFT/TDDFT. Chem. Select. 2018, 3, 1623 – 1628
Sagar Arepally, Venkata Nagarjuna Babu, Manickam Bakhadoss and Duddu S. Sharada. A Direct Cycloaminative Approach to Imidazole Derivatives via Dual C-H Functionalization. Org lett. 2017, 19, 5014–5017.
Arumugavel Murugan, Shinde Vidyacharan, Ruma Ghosh and Duddu S. Sharada. Metal-Free Regioselective Dual C-H Functionalization in a Cascade Fashion: Access to Isocryptolepine Alkaloid Analogues. Chem. Select. 2017, 2, 3511–3515.
Shinde Vidyacharan, Chandan Adhikari, Vagolu Siva Krishna, Rudraraju Srilakshmi Reshma, Dharmarajan Sriram, and Duddu S. Sharada. A Robust Synthesis of Functionalized 2H-Indazoles via Solid State Melt Reaction (SSMR) and their Anti-tubercular Activity. Bioorg. Med. Chem. Lett. 2017, 27, 1593-1597.
Anand H Shinde, Sagar Arepally, Mayur D. Baravkar and Duddu S. Sharada. Nickel-Catalyzed Aerobic Oxidative Isocyanide Insertion: Access to Benzimidazoquinazoline Derivatives via Sequential Double Annulation Cascade (SDAC) strategy. J. Org. Chem. 2016, 82, 331-342.
A. Sagar, Venkata Nagarjuna Babu, Anand H. Shinde and Duddu S. Sharada. A metal-free cyclic iminium induced one-pot double annulation cascade: access to dihydroisoquinolinium (DHIQ) salts. Org. Biomol. Chem. 2016, 14, 10366-10370.
Duddu S. Sharada, Anand H Shinde, Srilaxmi M. Patel, and Shinde Vidyacharan. Scaffold Diversity through a Branching Double Annulation Cascade Strategy: An Iminium Induced One-pot Synthesis of Diverse Fused Tetrahydroisoquinoline (THIQ) Scaffolds. J. Org. Chem. 2016, 81, 6463-6471.
A. Sagar, Shinde Vidyacharan, Anand H. Shinde and Duddu S. Sharada. Hypervalent Iodine(III)-Mediated Dehydrogenative Nitrogenation of N-Aryl Vinylogous Carbamates to Quinoxalines in Cascade Fashion: Access to 1, 4, 5, 8-Tetraazaphenanthrene. Org. Biomol. Chem. 2016, 14, 4018-4022.
Shinde Vidyacharan, Arumugavel Murugan, and Duddu S. Sharada. C(sp2)−H Functionalization of 2H−indazoles at C3-position via palladium(II)−catalyzed isocyanide insertion strategy leading to diverse heterocycles. J. Org. Chem. 2016, 81, 2837-2848.
Anand H. Shinde, Shinde Vidyacharan and Duddu S. Sharada. BF3·OEt mediated metal-free one-pot sequential multiple annulation cascade (SMAC) synthesis of complex and diverse tetrahydroisoquinoline fused hybrid molecules. Org. Biomol. Chem. 2016, 14, 3207-3211. (Selected in synfacts for its important highlights, Issue 07/2016)
Shinde Vidyacharan, A. Sagar, Duddu S. Sharada. A new route for the synthesis of highly substituted 4-aminoquinoline drug like molecules via aza hetero–Diels–Alder reaction. Org. Biomol. Chem. 2015, 13, 7614-7618.
A. Sagar, Venkata Nagarjuna Babu, Arnab Dey, Duddu S. Sharada. I2-promoted denitration strategy: one-pot three component synthesis of pyrrole-fused benzoxazine. Tetrahedron Lett. 2015, 56, 2710–2713.
A. Sagar, Venkata Nagarjuna Babu, Arnab Dey, Duddu S. Sharada. Silica gel promoted environment-friendly synthesis of α-amino amidines and regioselective transformation of α-amino amidines into amidino substituted indazoles. RSC Adv. 2015, 5, 29066-29071.
Shinde Vidyacharan, Chaitra C., A. Sagar, Duddu S. Sharada. A one-pot palladium catalysed ligand and metal oxidant-free oxidative isocyanide insertion leading to 2-amino-substituted-4(3H)-quinozolinones. Synth. Commun. 2014, 45, 898-907.
Anand H. Shinde, Archith. N, Srilaxmi malipatel, Duddu S. Sharada. A facile one-pot protocol for the synthesis of tetrazolyl-tetrahydroisoquinolines via novel domino intramolecular cyclization/Ugi-azide sequence. Tetrahedron let. 2014, 55, 6821-6826.
Anand H. Shinde, Srilaxmi malipatel, Bishnupada Satpathi, Duddu S. Sharada. A highly efficient synthesis of imidazo-fused polyheterocycles via Groebke-Blackburn-Bienaym reaction catalyzed by LaCl3.7H2O. Tetrahedron let. 2014, 55, 5915-5920.
A. Sagar, Shinde Vidyacharan, Duddu S. Sharada. I2-promoted cross-dehydrogenative coupling of a carbonyl aldehydes with alcohols for the synthesis of a-ketoesters. RSC Adv. 2014, 4, 37047-37050.
Shinde Vidyacharan, A. Sagar, Chaitra C., Duddu S. Sharada. A facile synthesis of 2H-indazoles under neat conditions and further transformation into aza-g-carboline alkaloid analogues in a tandam one-pot fashion. RSC Adv. 2014, 65, 34232-34236.
Anand H. Shinde, Shinde Vidyacharan, Duddu S. Sharada. Microwave-assisted facile synthesis of [a]-annelated pyrazolopyrroloindoles via intramolecular azomethine imine 1,3-dipolar cycloaddition. Tetrahedron let. 2014, 55, 3064-3069.
Shinde Vidyacharan, Anand H. Shinde, Bishnupada Satpathi, Duddu S. Sharada. A Facile protocol for the Synthesis of 3-Aminoimidazo-Fused Heterocycles via Groebke-Blackburn-Bienayme Reaction Under Catalyst-Free and Solvent-Free Conditions. Green Chem. 2014, 16, 1168-1175.
Manickam Bakthadoss, Govindan Sivakumar, Duddu S. Sharada, Highly Regio- and Stereoselective Synthesis of Tetracyclic Indolenoisoxazolidine via Intramolecular 1,3-Dipolar Nitrone Cycloadditions. Synthesis. 2013, 45, 237–245.
Manickam Bakthadoss, Nagappan Sivakumar, Anthonisamy Devaraj, Duddu S. Sharada, 1,3-Dipolar Cycloaddition on Baylis-Hillman Adducts: Novel Synthesis of Pyrrolidines, Spiropyrrolidines and Spiropyrrolizidines. Synthesis. 2011, 13, 2136-2146.
Deevi Basavaiah, Duddu S. Sharada, Ainelly Veerendhar Organo-base mediated Cannizzaro reaction. Tetrahedron Lett. 2006, 47, 5771-5774.
I. Schmidt, J. Jiao, P. Thamyongkit, Duddu S. Sharada, D. F. Bocian, J. S. Lindsey, Investigation of Stepwise Covalent Synthesis on a Surface Yielding Porphyrin-Based Multicomponent Architectures. J. Org. Chem. 2005, 71, 3033-3050.
K. Muthukumaran, H. Z. Syeda Huma, Y. Lianhe, P. Thamyongkit, M. E. Calder, Duddu S. Sharada, J. S. Lindsey, Synthesis of dipyrrin-containing architectures, J. Porphyrins Phthalocyanines, 9, 745-759., 2005.
Duddu S. Sharada, Ana Z. Muresan, Kannan. Muthukumaran, J. S. Lindsey, Direct synthesis of palladium porphyrins from acyldipyrromethanes. J. Org. Chem. 2005, 70, 3500-3510.
D. Basavaiah, Duddu S. Sharada , A. Veerendhar, A facile tandem construction of C-O and C-C bonds: a novel one-pot transformation of Baylis-Hillman adducts into 2-benzoxepines. Tetrahedron Lett, 2004, 45, 3081-3083.
D. Basavaiah, Duddu S. Sharada, N. Kumragurubaran, R. Mallikarjuna Reddy, The Baylis-Hillman Reaction: One-Pot Facile Synthesis of 2,4-Functionalized 1,4-Pentadienes. J. Org. Chem. 2002, 67 ,7135-7137.
D. Basavaiah, R. Mallikarjuna Reddy, N. Kumragurubaran, Duddu S. Sharada, Applications of Baylis-Hillman chemistry: one-pot convenient synthesis of functionlized (1H)-quinol-2-ones and quinolines. Tetrahedron. 2002, 58, 3693-369.
D. Basavaiah, N. Kumragurubaran, Duddu S. Sharada, Baylis-Hillman chemistry: a novel synthesis of functionalized 1,4-pentadienes. Tetrahedron Lett. 2001, 42, 85-87.
D. Basavaiah, N. Kumragurubaran, Duddu S. Sharada, R. Mallikarjuna Reddy Applications of Baylis-Hillman chemistry: enantioselective synthesis of (-)-methyl3-aryl-2-methylene-3-(prop-2-yn-1-yloxy)propanoates via chiral leaving group strategy. Tetrahedron. 2001, 57, 8167-8172.
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Two Step, One-Pot Sequential Synthesis of Functionalized Hybrid Polyheterocyclic Scaffolds via Solid State Melt Reaction . RSC Advance,2019, 9, 24314 -24318.
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Bakthadoss M, Reddy TT, Agarwal V, Sharada DS. Ester directed orthogonal dual CH activation and ortho aryl CH alkenylation via distal weak coordination. Chemical Communications. 2022.
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Bakthadoss M, Mushaf M, Agarwal V, Reddy TT, Sharada DS. Azomethine ylide cycloaddition of 1, 3-dienyl esters: highly regio-and diastereoselective synthesis of functionalized pyrrolidinochromenes. Organic & Biomolecular Chemistry. 2022.